DR. DEVLINA GHOSH
Introduction and Education
Dr. Devlina Ghosh, Ph.D., MBA, MSc (Biochemistry) Gold Medallist is an Assistant Professor of Biochemistry at Saraswati Dental College and Hospital, Lucknow, India. She worked as Senior Research Specialist at the Johns Hopkins University, School of Medicine, Baltimore, USA for more than 8 years. She has published many research papers in high impact scientific journals such as Nature Methods, Nature Communication, Proceedings of the National Academy of Sciences (PNAS) among others. Her research interests lie at the intersection of inflammation, macrophage activation, and metabolic regulation, particularly understanding the intricate mechanisms underlying immune cell activation and their role in the pathophysiology of inflammatory diseases.
Some of her key publications are-
1. Alok Kumar, Gajendra Singh, Francesco Zonta, Qiujie Zhu, Anjali Singh, Abhishek Saxena, Devlina Ghosh. Targeting phospholipase A2 with arachidonyl trifluoromethyl ketone modulates macrophage activation during Japanese encephalitis virus infection. Med Microbiol Immunol 215, 18 (2026). https://doi.org/10.1007/s00430-026-00879-x Impact Factor: 3.0
2. Devlina Ghosh, Jia Wang, Weihuan Wen, Abhishek Saxena, Alok Kumar. FcRn-targeted therapeutics: Neonatal fc receptor at the interface of balancing immune modulation and persevering protective humoral immunity. Int Immunopharmacol. 2026;182:116751. https://doi.org/10.1016/j.intimp.2026.116751 Impact Factor: 4.7
3. Devlina Ghosh*, Anshika Yadav, Damini Pandey. Immunomodulatory roles of gut-derived short-chain fatty acids in periodontal inflammation and homeostasis. Explor Immunol. 2026;6:1003238. https://doi.org/10.37349/ei.2026.1003238 *Corresponding Author
4. Devlina Ghosh*, Alok Kumar. Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement. World J Hepatol 2025; 17(12): 115551; DOI: https://dx.doi.org/10.4254/wjh.v17.i12.115551 *Corresponding Author, Impact Factor: 2.5
5. Devlina Ghosh*, Alok Kumar. The Role of Oral Microbiota and Glial Cell Dynamics in Relation to Gender in Cardiovascular Disease Risk. Neuroglia 2025, 6(3), 30; https://doi.org/10.3390/neuroglia6030030 *Corresponding Author
6. Devlina Ghosh*, Alok Kumar. Harnessing Mitophagy for Therapeutic Advances in Aging and Chronic Neurodegenerative Diseases. Neuroglia 2024, 5(4), 391-409; https://doi.org/10.3390/neuroglia5040026 *Corresponding Author
7. Devlina Ghosh*, Alok Kumar. Chapter 11- Anxiety and Depression-Related Problems Associated with Adolescents. Editors : Aditi Singh and Abhishek Nandy, Lifestyle Diseases in Adolescents: Addressing Physical, Emotional and Behavioral Issues, Bentham Books 2024, Pages 158-178, ISBN 978-981-5274-40-0 DOI: 10.2174/9789815274400124010013 *Corresponding Author
8. Devlina Ghosh*, Gajendra Singh, Prabhaker Mishra, Aditi Singh, Alok Kumar, Neeraj Sinha. Alteration in mitochondrial dynamics promotes the proinflammatory response of microglia and is involved in cerebellar dysfunction of young and aged mice following LPS exposure, Neuroscience Letters, Volume 807, 2023, 137262, (IF 3.2) DOI: 10.1016/j.neulet.2023.137262 *Corresponding Author Impact Factor: 2.5
9. Devlina Ghosh*, Aditi Singh , Alok Kumar , Neeraj Sinha. High mobility group box 1 (HMGB1) inhibition attenuates lipopolysaccharide-induced cognitive dysfunction and sickness-like behavior in mice. Immunologic Research 70, 633–643 (2022) (IF 4.4) DOI: 10.1007/s12026-022-09295-8 *Corresponding Author, Impact Factor: 3.1
10. Devlina Ghosh*, Aditi Singh, Neeraj Sinha, Chapter 2 - Immunological Genes Expression in the Aged Brain, Editor: Sunil Kumar, The Molecular Immunology of Neurological Diseases, Academic Press, 2021, Pages 15-27, ISBN 9780128219744 https://doi.org/10.1016/B978-0-12-821974-4.00005-4 *Corresponding Author
11. Devlina Ghosh*, Alok Kumar, Neeraj Sinha, Chapter 6 - Targeted genome editing: a new era in molecular biology, Editors: Sukanta Mondal, Ram Lakhan Singh, Advances in Animal Genomics, Academic Press, 2021, Pages 75-89, ISBN 9780128205952 Thttps://doi.org/10.1016/B978-0-12-820595-2.00006-0 *Corresponding Author
12. Devlina Ghosh, Bingxin Bai , Qun Ji , Soumya Palliyil , Guang Yang , Alok Kumar, Abhishek Saxena, State-of-the-art preclinical evaluation of COVID-19 vaccine candidates. Exploration of Immunology 2021;1:440-60. DOI: https://doi.org/10.37349/ei.2021.00030
13. Jonathan P Ling, Christopher Wilks, Rone Charles, Devlina Ghosh, Lizhi Jiang, Clayton P., Santiago, Bo Pang, Anand Venkataraman, Brian S Clark, Abhinav Nellore, Ben Langmead, Seth Blackshaw. ASCOT identifies key regulators of neuronal subtype-specific splicing. Nature Communications (Reference Number: NCOMMS-19-15158) 2020 Jan 9;11(1):137. DOI: 10.1038/s41467-019-14020-5 Impact Factor: 15.7
14. GuanDa Syu, ShihChin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash,Brandon Henson, LienChun Weng, Devlina Ghosh, Pedro Ramos, Daniel Eichinger, Ignacio Pino, Xinzhong Dong, Jie Xiao, Shaopeng Wang, Nongjian Tao, Kwang Sik Kim, Prashant J. Desai, Heng Zhu. Development and Application of a High-Content Virion Display Human GPCR Array. Nature Communications (Reference number: NCOMMS-18-27774), 2019, DOI: 10.1038/s41467-019-09938-9 Impact Factor: 15.7
15. Anand Venkataraman, Kun Yang, Jose Irrizary, Mark Mackiewicz, Paolo Mita, Zheng Kuang, Lin Xue, Devlina Ghosh, Shuang Liu, Pedro Ramos, Shaohui Hu, Diane Bayron, Sarah Keegan, Richard Saul, Simona Colantonio, Hongyan Zhang, Florencia Pauli Behn, Guang Song, Edisa Albino, Lillyan Asencio, Leonardo Ramos, Luvir Lugo, Gloriner Morell, Javier Rivera, Kimberly Ruiz, Ruth Almodovar, Luis Nazario, Keven Murphy, Ivan Vargas, Zully Rivera-Pacheco, Christian Rosa, Moises Vargas, Jessica McDade, Brian S Clark, Sooyeon Yoo, Seva G Khambadkone, Jimmy de Melo, Milanka Stevanovic, Lizhi Jiang, Yana Li, Wendy Y Yap, Brittany Jones, Atul Tandon, Elliot Campbell, Stephen Anderson, Richard M Myers, Jef D Boeke, David Fenyo, Gordon Whiteley, Joel S Bader, Daniel J Eichinger, Ignacio Pino, Heng Zhu,Seth Blackshaw. A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors. Nature Methods, NMETH-RS30540, 2018, DOI: 10.1038/nmeth.4632 Impact Factor: 32.1
16. Amy F. Weil, Devlina Ghosh, Yan Zhou, Lauren Seiple, Moira A. McMahon, Adam M. Spivak, Robert F. Siliciano and James T. Stivers. Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration. Proceedings of the National Academy of Sciences of the United States of America. 5;110(6):E448-57. doi: 10.1073/pnas.1219702110. Epub 2013, DOI: 10.1073/pnas.1219702110 Impact Factor: 9.1
17. Alok Kumar*, Devlina Ghosh*, Ram Lakhan Singh. Amyotrophic Lateral Sclerosis and Metabolomics: Clinical Implication and Therapeutic Approach. Journal of Biomarker, 2013. DOI: 10.1155/2013/538765 * Authors equally contributed
18. Abhishek Singh, Puneet Ahuja, Rahul Chaurasia, Devlina Ghosh, Sneha Sinha, Shubhangi Mhaske. Microvascular Dysfunction In Hypertensive Denture Wearers: A Comprehensive Review Of Doppler And Optical Coherence Tomography Findings. Vegueta. Anuario de la Facultad de Geografía e Historia 26 (1), 2026 eISSN: 2341-1112 https://vegueta.org/index.php/VEG/article/view/153
Expertise and Thrust Area
Inflammation, Immunology, Neuroinflammation, Microglia/Macrophage Activation
Dr. Devlina Ghosh's research interests lie at the intersection of inflammation, macrophage activation, and metabolic regulation. She is particularly focused on unraveling the complex mechanisms by which macrophages and their central nervous system counterparts, microglia, become activated and contribute to immune-mediated pathophysiology. By studying the dynamic interplay between immune cell activ...








